The effects of montelukast on random pattern skin flap survival: An experimental study in rats
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چکیده
منابع مشابه
Favorable effects of progesterone on skin random flap survival in rats
Objective(s): The aim of this study is to determine the effects of progesterone treatment on the survival of random skin flaps. Materials and Methods: McFarlane flaps were established and 40 male rats were randomly assigned to the progesterone-treated as the test group or normal saline-treated as the control group. Progesterone or normal saline (10 mg/kg) was administered intraperitoneally onc...
متن کاملOral administration of alanyl-glutamine and glutamine improve random pattern dorsal skin flap survival in rats
Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
متن کاملEffects of calcitriol on random skin flap survival in rats
Calcitriol, a metabolite of vitamin D, is often used in osteoporosis clinics. However, the material has other bioactivities; for example, it accelerates angiogenesis, has anti-inflammatory properties, and inhibits oxidative stress. We investigated the effects of calcitriol in a random skin flap rat model. "McFarlane flap" models were established in 84 male Sprague Dawley rats, divided into two ...
متن کاملEffects of systemic chlorogenic acid on random-pattern dorsal skin flap survival in diabetic rats.
There has been considerable interest in understanding the effects of antioxidants in flap survival during diabetes. Previous studies showed that chlorogenic acid (CGA) exhibits potent antioxidant effects. We aimed to determine the effects of systemic CGA treatment on skin flap survival in an experimental random-pattern dorsal skin flap model in diabetic rats. Twenty-eight male Wistar rats were ...
متن کاملEffects of insulin-like growth factor-1 on random pattern skin flap survival in rats.
PURPOSE To investigate the effects of pharmacological delay with insulin-like growth factor-1 (IGF-1) on skin flap survival. METHODS Thirty Sprague-Dawley rats were submitted to dorsal skin flap (3x9 cm). Seven days before the surgery, the animals were subdivided into three groups of 10 rats. In group 1 (controls), no injection was done. Seven days before the elevation, saline had been inject...
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ژورنال
عنوان ژورنال: Current Therapeutic Research
سال: 2008
ISSN: 0011-393X
DOI: 10.1016/j.curtheres.2008.10.003